Since fleeing Augsburg, executioner’s daughter Elisa and her husband Matthias Eggenberger have lived a peaceful life in Venice. While Elisa tries to reduce the misery in the town with her healing powers, Matthias is successfully running the business of Augsburg merchant Konrad Rehlinger. However, when intrigues against Rehlinger are afoot, he travels to see Matthias in Venice in order to stop the activities of his opponent. Battista Motracchi, member of the Venetian nobility, is obsessed with eliminating his competitor Rehlinger and his employee Matthias Eggenberger, and winning over beautiful Elisa.